Details
GAP27, a peptide derived from the selective gap junction blocker connexin 43, inhibits gap junction signaling in endothelial cells. GAP27 also attenuates ACh-induced arterial relaxation and reduces K⁺-mediated smooth muscle repolarization in endothelium-intact vessels in vitro.
Item Number4095532APC Number54-1-42One Letter CodeSRPTEKTIFIISynonymsGap Junction α-1 Protein (200-210) (human, mouse, rat), Connexin 43 (200-210) (human, mouse, rat), Cx43 (200-210) (human, mouse, rat)Molecular FormulaC₆₀H₁₀₁N₁₅O₁₇Relative Molecular Mass1304.53CAS Registry Number[198284-64-9] netSourceSyntheticStorage Conditions-20 ± 5 °CAreas of Interest Regenerative Medicine Links / Documents:
Brochures:
No brochures found. Bachem product citations
J.Vecera et al., Comp. Biochem. Physiol. C. Toxicol. Pharmacol., 155, 389 (2012)
Product citations
G.R.Richards et al., Br. J. Pharmacol., 134, 1 (2001) K.Ko et al., Am. J. Physiol., Cell Physiol., 279, C147 (2000) J.T.Chaytor et al., J. Physiol., 503, 99 (1997)
