Details
The Flemish mutation (A21G) shows a decreased tendency to aggregate and a reduced neurotoxicity. A21G is pathogenic as it is degraded significantly more slowly by neprilysin than WT Abeta42.
Item Number4039930One Letter CodeDAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVVIASynonymsAmyloid β-Protein (1-42) Flemish Mutation, Amyloid β-Protein (1-42) A21G, Amyloid-beta Peptide (1-42), A21G, Human, Amyloid-beta Protein (1-42) (human), Flemish Mutation, [Gly21] - beta - Amyloid (1 - 42), [Gly21]-Abeta (1-42), HumanMolecular FormulaC₂₀₂H₃₀₉N₅₅O₆₀SRelative Molecular Mass4500.08SourceSyntheticStorage Conditions-20 ± 5 °CAreas of Interest Alzheimers Disease Links / Documents:
Brochures:
- Amyloid Peptides
- Care and Handling of Amyloid Peptides
Product citations
M.Yagi-Utsumi and C.M.Dobson, Biol. Pharm. Bull., 38, 1668 (2015) A.Huet and P.Derreumaux, Biophys. J., 91, 3829 (2006)
