Details
FK-13,coresequenceofLL-37,isprotectedfrombacterialproteolysisbyactin.FK-13showedactivityagainstHIV-1,EC₅₀3.4μM.AsremovaloftheN-terminalphenylalanineleadstoinactivation,FKRIVQRIKDFLRcorrespondstotheminimalanti-HIVregionofhumanLL-37.
ItemNumber4099695
OneLetterCodeFKRIVQRIKDFLR
SynonymsLL-37(17-29),CationicAntimicrobialProtein18(150-162)(human),hCAP18(150-162)ANDLL17-29
MolecularFormulaC₈₀H₁₃₅N₂₅O₁₇
RelativeMolecularMass1719.11
CASRegistryNumber[717919-68-1]net
SourceSynthetic
StorageConditions-20±5°C
AreasofInterestAntimicrobial&AntiviralPeptides
InfectiousDisease
Virology
Productcitations
A.Soletal.,RCSAdv.,5,9361(2015)
G.Wangetal.,Antimicrob.AgentsChemother.,52,3438(2008)