Details
GAP27,apeptidederivedfromtheselectivegapjunctionblockerconnexin43,inhibitsgapjunctionsignalinginendothelialcells.GAP27alsoattenuatesACh-inducedarterialrelaxationandreducesK⁺-mediatedsmoothmusclerepolarizationinendothelium-intactvesselsinvitro.
ItemNumber4095532
APCNumber54-1-42
OneLetterCodeSRPTEKTIFII
SynonymsGapJunctionα-1Protein(200-210)(human,mouse,rat),Connexin43(200-210)(human,mouse,rat),Cx43(200-210)(human,mouse,rat)
MolecularFormulaC₆₀H₁₀₁N₁₅O₁₇
RelativeMolecularMass1304.53
CASRegistryNumber[198284-64-9]net
SourceSynthetic
StorageConditions-20±5°C
AreasofInterestRegenerativeMedicine
Bachemproductcitations
J.Veceraetal.,Comp.Biochem.Physiol.C.Toxicol.Pharmacol.,155,389(2012)
Productcitations
G.R.Richardsetal.,Br.J.Pharmacol.,134,1(2001)
K.Koetal.,Am.J.Physiol.,CellPhysiol.,279,C147(2000)
J.T.Chaytoretal.,J.Physiol.,503,99(1997)