Details
ThesecretionofthecardiachormoneBNP-32isincreasedconsiderablyinpatientswithcongestiveheartfailure,successfulmedicaltreatmentofthisconditionwillresultinadecrease.Yandleetal.describedamethodfordetermininghBNPinhumanplasma.EffectsofhBNPinfusioninhumanshavebeendescribedbyHolmesetalandLaVillaetal.BNPisanimportantbio
Markerinthediagnosisofheartdiseases.Additionally,BNP-32mayactasaneuropeptide.
BNP-32exertsstronglipolyticeffectsinhumans.
ItemNumber4049848
OneLetterCodeSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
SynonymsNesiritide
MolecularFormulaC₁₄₃H₂₄₄N₅₀O₄₂S₄
RelativeMolecularMass3464.09
CASRegistryNumber[124584-08-3]net
SourceSynthetic
StorageConditions-20±5°C
KeywordsBiomarkerforcardiacdiseases;Lipolysis-inducingpeptide
AreasofInterestCardiovascularSystem&Diseases
RegenerativeMedicine
Bachemproductcitations
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Productcitations
J.Polaketal.,J.Am.Coll.Cardiol.,58,1119(2011)
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G.LaVillaetal.,J.Clin.Endocrinol.Metab.,78,1166(1994)
S.J.Holmesetal.,J.Clin.Endocrinol.Metab.,76,91(1993)
T.G.Yandleetal.,J.Clin.Endocrinol.Metab.,76,832(1993)
M.Mukoyamaetal.,J.Clin.Invest.,87,1402(1991)