Details
TheformationofamyloiddepositsbyIAPPcouldplayacentralroleinthepathogenesisoftypeIIdiabetes.Besidestheamyloidogenic20-29region,thedomainNFLVHSS(IAPP14-20)tendstoaggregateandseemstobeinvolvedinplaqueformation.
ItemNumber4099428
OneLetterCodeNFLVHSS
MolecularFormulaC₃₆H₅₄N₁₀O₁₁
RelativeMolecularMass802.89
CASRegistryNumber[121341-77-3]net
SourceSynthetic
StorageConditions-20±5°C
AreasofInterestDiabetes
Productcitations
S.GileadandE.Gazit,Exp.DiabetesRes.,2008,256954(2008)
L.A.Scrocchietal.,J.Struct.Biol.,141,218(2003)
Y.Mazoretal.,J.Mol.Biol.,322,1013(2002)